Maria Laura Martin Selected Research

2-hydroxyoleic acid

6/2014	Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.
5/2013	Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells.
5/2012	2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.
12/2011	Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.

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Maria Laura Martin Research Topics

Disease

8	Neoplasms (Cancer) 01/2022 - 12/2011
4	Glioma (Gliomas) 05/2013 - 12/2011
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2022
2	Adenoma (Adenomas) 01/2022 - 01/2018
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2022
1	Rectal Neoplasms (Rectal Cancer) 01/2022
1	Adenocarcinoma 01/2022
1	Colitis 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Bites and Stings (Sting) 01/2021
1	Carcinogenesis 01/2018
1	Sphingolipidoses (Sphingolipidosis) 05/2013
1	Lung Neoplasms (Lung Cancer) 05/2013

Drug/Important Bio-Agent (IBA)

4	2-hydroxyoleic acidIBA 06/2014 - 12/2011
3	Membrane LipidsIBA 06/2014 - 05/2012
3	SphingomyelinsIBA 05/2013 - 12/2011
2	phosphatidylcholine-ceramide phosphocholine transferaseIBA 05/2013 - 12/2011
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022
1	AzoxymethaneIBA 01/2022
1	HydrogelsIBA 01/2022
1	Leucine (L-Leucine)FDA Link 01/2022
1	Dextran SulfateIBA 01/2022
1	Androgen Receptors (Androgen Receptor)IBA 01/2022
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Adenosine (Adenocard)FDA LinkGeneric 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	SphingolipidsIBA 05/2013
1	Phospholipids (Phosphatides)FDA LinkGeneric 05/2013
1	Liposomes (Liposome)IBA 05/2013
1	Lipid Bilayers (Lipid Bilayer)IBA 05/2013
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2013
1	Antineoplastic Agents (Antineoplastics)IBA 05/2013
1	Temozolomide (Temodar)FDA LinkGeneric 05/2012
1	Pharmaceutical PreparationsIBA 05/2012

Therapy/Procedure

6	Therapeutics 01/2022 - 12/2011
1	Neoadjuvant Therapy 01/2022
1	Castration 01/2022
1	Drug Therapy (Chemotherapy) 01/2022
1	Immunotherapy 01/2021
1	Oral Administration 05/2012